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Structure of 209991-62-8
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3,4,5-Trifluorophenylacetic acid features a trifluorinated aromatic ring that imparts enhanced electron-withdrawing character and metabolic stability. This structure facilitates direct incorporation into bioactive molecules, enabling efficient conjugation in medicinal chemistry applications. The carboxylic acid group provides a reactive handle for amide bond formation under standard coupling conditions.
3,4,5-Trifluorophenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the introduction of a highly electron-deficient arylacetyl moiety into target molecules. Its trifluorophenyl group enhances metabolic stability and modulates lipophilicity, while the carboxylic acid functionality facilitates direct coupling reactions or derivatization. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, making it a practical choice for constructing bioactive scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: