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Structure of 210300-09-7
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3-Hydroxy-4-methoxypicolinic acid features a strategically positioned hydroxyl group and methoxy substituent on the picolinic scaffold, enabling robust coordination in metal complexation and enhancing solubility in polar solvents. This structural arrangement supports efficient integration into chelating ligands for catalytic applications and bioactive molecule scaffolds.
3-Hydroxy-4-methoxypicolinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and functionalized pyridine scaffolds. Its orthogonal functionality—bearing both phenolic hydroxyl and methoxy groups—facilitates selective derivatization, while the carboxylic acid enables amidation or esterification under standard conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it valuable for iterative synthesis campaigns targeting API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: