1-Boc-1-methylhydrazine

Name: 1-Boc-1-methylhydrazine
Brand: ChemScene
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CAS No. 21075-83-2
Cat. No. CS-W007496
Purity≥97%
MDL No.MFCD05669700

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

1-Boc-1-methylhydrazine is a bench-stable, moisture-tolerant hydrazine derivative featuring a tert-butoxycarbonyl-protected amine group. This protected form enables safe handling and controlled release of the active hydrazine moiety in synthetic workflows. It integrates seamlessly into peptide conjugation and heterocycle formation under standard conditions.

Application

1-Boc-1-methylhydrazine serves as a stable, bench-ready hydrazine equivalent for the introduction of methylhydrazino functionality in synthetic sequences. It enables selective N-alkylation and heterocycle formation under mild conditions, with excellent functional group tolerance and straightforward purification. The Boc group provides protection against undesired reactivity while allowing facile deprotection in acidic media, making it ideal for modular synthesis of nitrogen-rich scaffolds.

General Information

CAS No. 21075-83-2
Cat. No. CS-W007496
Purity ≥97%
MDL No. MFCD05669700
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₄N₂O₂
Molecular Weight 146.19
Synonym(s) tert-Butyl2-methylcarbazate; 1-Boc-1-methylhydrazine
SMILES NN(C(OC(C)(C)C)=O)C

Computational Chemistry Data

TPSA 55.56
LogP 0.727
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H302
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Hydrazine

Building Blocks Skeleton Fatty chain compounds

Key Words

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1-Boc-1-methylhydrazine

CAS No. 21075-83-2

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