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Structure of 21149-98-4
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5-(tert-Butyl)-1H-imidazole features a sterically hindered tert-butyl group at the 5-position, enhancing stability and solubility in organic media. This bench-stable imidazole derivative serves as a robust scaffold for catalytic systems and functional materials, offering improved resistance to decomposition under standard handling conditions.
5-(tert-Butyl)-1H-imidazole serves as a robust, bench-stable building block for heterocyclic synthesis, offering enhanced solubility and steric protection compared to unsubstituted imidazoles. Its functional group tolerance enables reliable use in transition-metal-catalyzed couplings, electrophilic substitutions, and as a scaffold in medicinal chemistry libraries. The tert-butyl group improves metabolic stability and facilitates purification through crystallization or chromatographic separation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: