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Structure of 21168-40-1
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2-(Quinolin-3-yl)acetic acid features a quinoline core linked to a carboxylic acid via a methylene bridge, enabling integration into bioactive scaffolds. The electron-deficient quinoline ring enhances π-stacking interactions, while the acidic moiety supports derivatization and metal chelation. This compound serves as a key intermediate in medicinal chemistry for targeting kinase pathways and modulating receptor binding.
2-(Quinolin-3-yl)acetic acid serves as a versatile building block for medicinal chemistry and materials science, enabling efficient access to bioactive heterocyclic scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization under standard conditions, while the quinoline core provides inherent metabolic stability and π-stacking potential. Bench-stable and readily purified by recrystallization, it functions reliably in peptide conjugation, Suzuki couplings, and functionalization of macrocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: