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Structure of 21169-71-1
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Isoxazole-5-carboxylic acid features a rigid, electron-deficient isoxazole ring fused to a carboxylic acid group, enabling direct incorporation into heterocyclic scaffolds. This bench-stable motif serves as a key building block in medicinal chemistry, particularly for bioactive compounds requiring metabolic stability and hydrogen-bonding capacity.
Isoxazole-5-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through established coupling and functionalization reactions. Its carboxylic acid group facilitates direct amidation, esterification, and metal-catalyzed transformations, while the isoxazole ring provides structural rigidity and metabolic stability. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for use in iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: