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Structure of 21172-41-8
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This trifluoromethyl-substituted aldehyde features a conjugated propionaldehyde chain attached to a meta-trifluoromethylphenyl ring, delivering enhanced electrophilicity and stability. The electron-withdrawing trifluoromethyl group modulates reactivity, enabling selective transformations in synthetic routes. Ideal for constructing bioactive scaffolds and functionalized intermediates in medicinal chemistry.
3-(3-Trifluoromethylphenyl)propionaldehyde serves as a versatile building block for the synthesis of biologically active compounds and functional materials. Its aldehyde functionality enables efficient imine formation, reductive amination, and coupling reactions under standard conditions. The trifluoromethylphenyl group imparts enhanced metabolic stability and lipophilicity, making it valuable in medicinal chemistry lead optimization. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: