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Structure of 21202-42-6
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4-(1H-Imidazol-2-yl)pyridine features a rigid, planar architecture combining a pyridine ring with an imidazole moiety, enabling strong π-stacking and metal coordination. This bifunctional scaffold integrates seamlessly into catalytic systems and ligand design, offering enhanced stability and tunable electronic properties in transition metal complexes.
4-(1H-Imidazol-2-yl)pyridine serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via palladium-catalyzed cross-coupling reactions. The imidazole moiety offers strong hydrogen bonding and metal coordination capacity, while the pyridine nitrogen provides a robust site for metallation or further functionalization. Its bench-stable, crystalline nature facilitates handling and purification, making it ideal for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: