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CS-W001157 4
Total: USD 88.00

3-Chloropyrazine-2-carboxamide

  • CAS No. 21279-62-9

  • Cat. No. CS-W003668
  • Purity≥98%
  • MDL No.MFCD09863915
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Chloropyrazine-2-carboxamide|CS-W003668

Structure of 21279-62-9

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Description

3-Chloropyrazine-2-carboxamide is a heterocyclic amide featuring a chlorinated pyrazine core with a carboxamide functionality at the 2-position. This scaffold delivers enhanced electron-withdrawing character and improved metabolic stability, making it valuable for medicinal chemistry applications in kinase inhibitor development and pharmaceutical lead optimization.

Application

3-Chloropyrazine-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazine-based heterocycles through nucleophilic substitution and cross-coupling reactions. Its chlorine and amide functionalities offer orthogonal reactivity for downstream functionalization, while its bench-stable crystalline form facilitates handling and purification in synthetic workflows.

General Information

  • CAS No. 21279-62-9
  • Cat. No. CS-W003668
  • Purity ≥98%
  • MDL No. MFCD09863915
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄ClN₃O
  • Molecular Weight 157.56
  • Synonym(s) 3-Chloro-2-pyrazinecarboxaMide
  • SMILES NC(=O)c1nccnc1Cl

Computational Chemistry Data

  • TPSA   68.87
  • LogP   0.2289
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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