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Structure of 2128735-27-1
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N-Mal-N-bis(PEG4-NH-Boc) features a bis-PEGylated maleimide moiety with dual PEG4-NH-Boc protecting groups, enabling site-specific conjugation in aqueous environments. This derivative combines enhanced solubility and stability with controlled reactivity, facilitating efficient bioconjugation workflows under physiological conditions.
N-Mal-N-bis(PEG4-NH-Boc) serves as a versatile bifunctional linker for conjugation chemistry, combining maleimide reactivity with PEGylated amine protection. The maleimide group enables efficient, selective Michael addition with thiols under physiological conditions, while the PEG4-protected amines offer enhanced solubility and stability. This compound facilitates site-specific bioconjugation in antibody-drug conjugate (ADC) development and peptide-protein labeling, enabling straightforward purification and controlled release via deprotection.
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Lot numbers can be found on the outside label of a product: