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Structure of 2129-30-8
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This diphenylphosphino-substituted benzoic acid features a strategically positioned phosphine group that enhances metal coordination, enabling efficient ligand integration in catalytic systems. The carboxylic acid functionality supports conjugation and derivatization, while the electron-rich phosphine improves reactivity in cross-coupling processes.
3-(Diphenylphosphino)benzoic acid serves as a versatile bifunctional building block for transition-metal-catalyzed cross-coupling and ligand development. The carboxylic acid group enables direct derivatization via esterification or amide formation, while the diphenylphosphino moiety provides strong coordination to palladium and platinum centers. This dual functionality facilitates efficient synthesis of phosphine-containing heterocycles and functionalized biaryls, with excellent bench stability and straightforward purification by recrystallization or chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: