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Structure of 2141976-33-0
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endo-BCN-PEG3-mal features a reactive maleimide handle appended to a hydrophilic PEG3 spacer, enabling efficient conjugation with thiol-containing biomolecules. The strained cycloalkyne moiety facilitates rapid bioorthogonal ligation under physiological conditions, while the PEG3 linker enhances solubility and reduces aggregation. This compound is ideal for site-specific labeling in complex biological systems.
endo-BCN-PEG3-mal serves as a versatile, bifunctional crosslinker enabling site-specific conjugation in bioorthogonal workflows. The cyclooctyne (BCN) moiety undergoes rapid strain-promoted azide-alkyne cycloaddition (SPAAC), while the maleimide group selectively reacts with cysteine residues under physiological conditions. The PEG3 spacer provides enhanced solubility and reduced aggregation, improving performance in protein labeling and antibody-drug conjugate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: