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Structure of 214360-62-0
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2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine features a boronate ester group flanked by tetramethyl-substituted dioxaborolane rings, providing enhanced stability and moisture tolerance. This bench-stable reagent integrates readily into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under standard conditions. The pyridine scaffold offers directional control in heterocyclic synthesis, while the bromide facilitates selective functionalization.
2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. The pyridine core enables direct functionalization at the 5-position, while the stable, air-tolerant boronate ester facilitates efficient C–C bond formation with aryl and heteroaryl halides. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: