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Structure of 2145-27-9
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7-Fluoro-4-hydroxy-2H-chromen-2-one features a fluorinated chromenone core with a phenolic hydroxyl group, offering enhanced electronic effects and metabolic stability. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitors and fluorescent probes, due to its planar structure and polarity.
7-Fluoro-4-hydroxy-2H-chromen-2-one serves as a versatile scaffold for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its fluorinated chromenone core enables enhanced metabolic stability and modulated electronic properties, while the phenolic hydroxyl group facilitates direct derivatization or metal-catalyzed coupling reactions. The compound exhibits good bench stability and compatibility with standard purification techniques, making it a practical building block in medicinal chemistry campaigns targeting kinase inhibitors and CNS agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: