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Structure of 2146-61-4
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1-(2-Bromoethyl)-3-methoxybenzene features a bromoethyl chain appended to a methoxy-substituted benzene ring, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The electron-donating methoxy group enhances reactivity at the ortho position, while the terminal bromide offers high chemoselectivity for transition metal-catalyzed transformations. This compound serves as a key intermediate in synthesizing bioactive molecules and functional polymers.
1-(2-Bromoethyl)-3-methoxybenzene serves as a versatile synthetic building block for the construction of functionalized aromatic ethers and heterocyclic systems. The bromoethyl side chain enables efficient Suzuki, Negishi, and Sonogashira coupling reactions, while the methoxy group provides moderate electron-donating character and ortho-directing influence. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: