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Structure of 214701-49-2
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1-(5-Bromopyridin-2-yl)ethanone features a brominated pyridine ring coupled to an acetyl group, delivering a robust platform for cross-coupling and heterocyclic functionalization. The electron-deficient pyridine moiety enhances reactivity in palladium-catalyzed transformations, while the ketone function enables further derivatization via nucleophilic addition or enolization. This compound serves as a key building block in medicinal chemistry and materials synthesis.
1-(5-Bromopyridin-2-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The ketone functionality provides a handle for further functionalization, including enolization and nucleophilic addition, while the pyridine ring offers moderate basicity and coordination potential. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: