Fmoc-D-Lys(Aloc)-OH

Name: Fmoc-D-Lys(Aloc)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 214750-75-1
Cat. No. CS-W022726
Purity≥95%
MDL No.MFCD00798639

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 214750-75-1

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Description

Fmoc-D-Lys(Aloc)-OH features a D-lysine residue protected with both Fmoc and Aloc groups, enabling orthogonal deprotection during solid-phase peptide synthesis. The Aloc moiety offers selective removal under mild photocleavage conditions, preserving other functional groups. This dual protection strategy enhances synthetic flexibility in complex peptide assembly, particularly for multi-protected sequences requiring sequential deprotection.

Application

Fmoc-D-Lys(Aloc)-OH serves as a key building block in the synthesis of peptide-based therapeutics and combinatorial libraries. The Fmoc group enables efficient N-terminal protection in solid-phase peptide synthesis, while the Aloc (alloc) side chain protection offers orthogonal deprotection under mild palladium(0) conditions. This dual functionality facilitates selective modification and simplifies purification in complex sequences, making it ideal for site-specific conjugation and multi-step peptide assembly.

General Information

CAS No. 214750-75-1
Cat. No. CS-W022726
Purity ≥95%
MDL No. MFCD00798639
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₅H₂₈N₂O₆
Molecular Weight 452.50
Synonym(s) None
SMILES O=C(O)[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCCCNC(OCC=C)=O

Computational Chemistry Data

TPSA 113.96
LogP 4.0608
H_Acceptors 5
H_Donors 3
Rotatable_Bonds 11

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Lysine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-D-Lys(Aloc)-OH

CAS No. 214750-75-1

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