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Structure of 214760-18-6
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4-Acetyl-2-fluorobenzonitrile features a fluorinated aromatic ring bearing both acetyl and nitrile functionalities, enabling strategic integration into pharmaceutical intermediates. The electron-withdrawing nitrile group enhances reactivity at the adjacent carbonyl site, while the ortho-fluoro substituent imparts metabolic stability and modulates electronic properties. This combination facilitates efficient coupling reactions under mild conditions.
4-Acetyl-2-fluorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted heterocycles via cyclization reactions. Its ortho-fluoro and nitrile groups facilitate directed metallation and subsequent functionalization, while the acetyl group offers a handle for aldol-type condensations or reductive transformations. Bench-stable and compatible with standard reaction conditions, it supports scalable synthesis of complex scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: