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CS-W001157 4
Total: USD 88.00

Azido-PEG12-acid

  • CAS No. 2152679-71-3

  • Cat. No. CS-0115264
  • Purity≥96%
  • MDL No.MFCD21363301
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Azido-PEG12-acid|CS-0115264

Structure of 2152679-71-3

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Description

Azido-PEG12-acid is a bifunctional linker featuring a terminal azide group and a carboxylic acid moiety separated by a 12-ethylene glycol unit. This hydrophilic spacer enhances solubility while enabling bioorthogonal conjugation via strain-promoted or copper-catalyzed azide-alkyne cycloaddition. The acid functionality facilitates amide bond formation with amines, streamlining the synthesis of targeted probes and functionalized biomolecules under standard conditions.

Application

Azido-PEG12-acid serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining a terminal azide group with a carboxylic acid functionality. The PEG12 spacer provides enhanced solubility and reduced aggregation, while enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and amide coupling reactions. Its stability under standard bench conditions and compatibility with diverse functional groups make it ideal for constructing site-specific conjugates and functionalized materials in drug delivery and diagnostics.

General Information

  • CAS No. 2152679-71-3
  • Cat. No. CS-0115264
  • Purity ≥96%
  • MDL No. MFCD21363301
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₅₃N₃O₁₄
  • Molecular Weight 643.72
  • Synonym(s) None
  • SMILES OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Computational Chemistry Data

  • TPSA   196.82
  • LogP   0.9706
  • H_Acceptors   14
  • H_Donors   1
  • Rotatable_Bonds   39

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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