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Structure of 2152679-71-3
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Azido-PEG12-acid is a bifunctional linker featuring a terminal azide group and a carboxylic acid moiety separated by a 12-ethylene glycol unit. This hydrophilic spacer enhances solubility while enabling bioorthogonal conjugation via strain-promoted or copper-catalyzed azide-alkyne cycloaddition. The acid functionality facilitates amide bond formation with amines, streamlining the synthesis of targeted probes and functionalized biomolecules under standard conditions.
Azido-PEG12-acid serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining a terminal azide group with a carboxylic acid functionality. The PEG12 spacer provides enhanced solubility and reduced aggregation, while enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and amide coupling reactions. Its stability under standard bench conditions and compatibility with diverse functional groups make it ideal for constructing site-specific conjugates and functionalized materials in drug delivery and diagnostics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: