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Structure of 215433-19-5
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7-Bromo-5-chloroindolin-2-one features a fused tricyclic core with halogenated substituents at the 7 and 5 positions, imparting enhanced electron-withdrawing character. This configuration supports stable integration into synthetic scaffolds for medicinal chemistry campaigns, particularly in kinase inhibitor development and bioactive heterocycle design.
7-Bromo-5-chloroindolin-2-one serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indole scaffolds. Its bromo and chloro substituents provide orthogonal handles for palladium-catalyzed cross-coupling reactions, while the ketone functionality supports enolate formation and electrophilic substitution. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: