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Structure of 215801-73-3
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8-Fluoroquinoline-4-carboxylic acid features a fluorine atom at the 8-position and a carboxylic acid group at the 4-position, creating a rigid, electron-deficient heterocyclic scaffold. This combination enhances solubility in polar solvents and enables direct coupling reactions without protective group manipulation. The molecule integrates readily into pharmaceutical intermediates and functional materials requiring defined electronic properties.
8-Fluoroquinoline-4-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical research. Its electron-deficient quinoline core enables efficient coupling reactions via the carboxylic acid group, while the 8-fluoro substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for use in standard amide coupling, Suzuki-Miyaura, and direct arylation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: