4-(tert-Butyl)3-methyl(S)-morpholine-3,4-dicarboxylate

Name: 4-(tert-Butyl)3-methyl(S)-morpholine-3,4-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 215917-98-9
Cat. No. CS-0171820
Molecule weight245.27
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(tert-Butyl)3-methyl(S)-morpholine-3,4-dicarboxylate|CS-0171820

Structure of 215917-98-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 215917-98-9
Cat. No. CS-0171820
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₅
Molecular Weight 245.27
Synonym(s) (S)-4-tert-butyl 3-methyl morpholine-3,4-dicarboxylate
SMILES CC(C)(C)OC(=O)N1CCOC[C@H]1C(=O)OC

Description

This chiral morpholine derivative features a tert-butyl group and a methyl substituent at the 4- and 3-positions, respectively, with the (S)-configuration at the 3-position. The dicarboxylate functionality enables efficient incorporation into synthetic scaffolds, particularly in medicinal chemistry applications requiring stereochemical control. Bench-stable and moisture-tolerant, it serves as a robust building block for complex heterocyclic systems.

Application

4-(tert-Butyl)3-methyl(S)-morpholine-3,4-dicarboxylate serves as a stereochemically defined morpholine scaffold for medicinal chemistry campaigns, enabling direct incorporation into bioactive molecules via standard coupling protocols. The tert-butyl ester group provides bench stability and orthogonal deprotection under mild acidic conditions, while the methyl and carboxylate functionalities offer controlled reactivity for amide formation and further functionalization. Functions as a key building block in the synthesis of heterocyclic APIs and kinase inhibitors.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 65.07
LogP 0.7953
H_Acceptors 5
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

215917-98-9 sigma215917-98-9 manufacturer215917-98-9 price215917-98-9 structure215917-98-9 SDSbuy 215917-98-9215917-98-9 supplier215917-98-9 uses215917-98-9 molecular weightprice of 215917-98-9215917-98-9 chemical name formula of 215917-98-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-(tert-Butyl)3-methyl(S)-morpholine-3,4-dicarboxylate

CAS No. 215917-98-9

Recommended Products