Lot numbers can be found on the outside label of a product:
3-(2-Naphthyl)propanoic Acid
-
CAS No. 21658-35-5
- Cat. No. CS-0155875
- Purity≥95%
- MDL No.MFCD00092742
*For research and further manufacturing use only, not for direct human use.
Structure of 21658-35-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 21658-35-5
- Cat. No. CS-0155875
- Purity ≥95%
- MDL No. MFCD00092742
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₃H₁₂O₂
- Molecular Weight None
- Synonym(s) 3-(Naphthalen-2-yl)propanoic acid
- SMILES C1=CC=C2C=C(C=CC2=C1)CCC(=O)O
Description
3-(2-Naphthyl)propanoic acid features a rigid, planar naphthyl ring system conjugated to a propionic acid side chain, enhancing its utility in constructing bioactive molecules. This structure imparts high stability and favorable solubility in organic solvents, enabling efficient incorporation into pharmaceutical intermediates and functional materials under standard conditions.
Application
3-(2-Naphthyl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its rigid naphthalene moiety imparts favorable π-stacking interactions, while the aliphatic carboxylic acid facilitates derivatization via esterification, amide formation, or activation for cross-coupling. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for high-throughput synthesis and process development workflows.
Synthesis
-
Route1
-
In-stock
51557-26-7 - ~67%
-
In-stock
21658-35-5
References
-
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.; PRESIDENT AND FELLOWS OF HARWARD COLLEGE; YALE UNIVERSITY Patent: WO2008/156701 A2, 2008 ; Location in patent: Page/Page column 44; 45-46 ;
-
-
Route2
-
141-82-2 -
In-stock
66-99-9 - ~88%
-
In-stock
21658-35-5
References
-
Kita; Higuchi; Yoshida; Iio; Kitagaki; Ueda; Akai; Fujioka Journal of the American Chemical Society, 2001 , vol. 123, # 14 p. 3214 - 3222
-
-
Route3
-
In-stock
49711-14-0 - ~%
-
In-stock
21658-35-5
References
-
Journal of Medicinal Chemistry, , vol. 30, # 3 p. 574 - 580
-
Safety Information
Download SDS|
GHS Pictogram :
N/A
|
GHS No : N/A
|
|
Signal Word : N/A
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : N/A
|
|
|
Precautionary Statements : N/A
|
|
Quality Control
Computational Chemistry Data
- TPSA 37.3
- LogP 2.857
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3-(2-Naphthyl)propanoic Acid sigma3-(2-Naphthyl)propanoic Acid manufacturer3-(2-Naphthyl)propanoic Acid price3-(2-Naphthyl)propanoic Acid structure3-(2-Naphthyl)propanoic Acid SDSbuy 3-(2-Naphthyl)propanoic Acid3-(2-Naphthyl)propanoic Acid supplier3-(2-Naphthyl)propanoic Acid uses3-(2-Naphthyl)propanoic Acid molecular weightprice of 3-(2-Naphthyl)propanoic Acid3-(2-Naphthyl)propanoic Acid chemical name formula of 3-(2-Naphthyl)propanoic Acid