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Structure of 2166008-44-0
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This chiral piperidine derivative features a bench-stable tert-butyl carbamate protecting group and two fluorine atoms at the 4-position, enhancing metabolic stability and modulating electronic properties. The carboxylic acid functionality enables direct coupling in peptide synthesis or further derivatization.
(R)-1-(tert-Butoxycarbonyl)-4,4-difluoropiperidine-2-carboxylic acid serves as a versatile chiral building block for the synthesis of fluorinated piperidine-containing scaffolds. The difluoropiperidine core imparts enhanced metabolic stability and modulates lipophilicity, while the Boc group enables straightforward deprotection and further functionalization. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into peptide-like compounds and medicinal chemistry libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: