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CS-W001157 4
Total: USD 88.00

(2R,3S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

  • CAS No. 21679-12-9

  • Cat. No. CS-0522560
  • Purity≥96%
  • MDL No.MFCD03411337

*For research and further manufacturing use only, not for direct human use.

(2R,3S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0522560

Structure of 21679-12-9

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General Information

  • CAS No. 21679-12-9
  • Cat. No. CS-0522560
  • Purity ≥96%
  • MDL No. MFCD03411337
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂FN₅O₃
  • Molecular Weight 269.23
  • Synonym(s) 2-Fluoro-2-Deoxyadenosine
  • SMILES O[C@H]1C[C@H](N2C=NC3=C(N=C(F)N=C32)N)O[C@@H]1CO

Synthesis

  • Route1
    • null|null
      259528-01-3
    • ~98%
    • (2R,3S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0522560
      21679-12-9

    References

    • Hassan, Abdalla E. A.; Shortnacy-Fowler, Anita T.; Montgomery, John A.; Secrist III, John A. Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 3 p. 559 - 565
  • Route2
    • null|null
      675598-20-6
    • ~85%
    • (2R,3S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol|CS-0522560
      21679-12-9

    References

    • Ye, Song; Rezende, Martha M.; Deng, Wei-Ping; Kirk, Kenneth L. Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 10 p. 1899 - 1905
  • Route3

    References

    • Nbile, Matas; Terreni, Marco; Lewkowicz, Elizabeth; Iribarren, Adolfo M. Biocatalysis and Biotransformation, 2010 , vol. 28, # 5-6 p. 395 - 402

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   119.31
  • LogP   -0.8117
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   2

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