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Structure of 216955-75-8
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6-(1H-Imidazol-1-yl)nicotinic acid integrates a bioactive imidazole moiety with a pyridine-carboxylic acid scaffold, offering enhanced solubility and hydrogen-bonding capacity. This structural motif enables efficient coordination in metal-complexing applications and facilitates incorporation into ligand frameworks for catalysis and medicinal chemistry.
6-(1H-Imidazol-1-yl)nicotinic acid serves as a versatile building block for heterocyclic synthesis, enabling the construction of bioactive scaffolds through standard coupling and cyclization protocols. The imidazole moiety provides strong hydrogen-bonding capacity and metal-chelating ability, enhancing target affinity in medicinal chemistry applications. Bench-stable and readily purified by recrystallization, it functions effectively in amide bond formation, Suzuki-Miyaura couplings, and transition-metal-catalyzed transformations, supporting scalable synthesis of functionalized pyridine derivatives.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: