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Structure of 2170881-31-7
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1-Isopropyl-3-(trifluoromethyl)pyrazole-4-boronic acid delivers a sterically hindered, electron-deficient boronate moiety ideal for Suzuki-Miyaura cross-coupling under standard conditions. The trifluoromethyl group enhances metabolic stability and modulates electronic properties, while the isopropyl substituent provides steric protection to the boronic acid functionality. This combination ensures high bench stability and compatibility with diverse reaction partners.
1-Isopropyl-3-(trifluoromethyl)pyrazole-4-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction conditions. Its orthogonal functionalization profile facilitates integration into complex molecular architectures relevant to medicinal chemistry and agrochemical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: