(4-(Pyridin-4-yl)phenyl)methanol

Name: (4-(Pyridin-4-yl)phenyl)methanol
Brand: ChemScene
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CAS No. 217192-22-8
Cat. No. CS-0157565
Purity≥98%
MDL No.MFCD04114576

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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(4-(Pyridin-4-yl)phenyl)methanol|CS-0157565

Structure of 217192-22-8

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Description

(4-(Pyridin-4-yl)phenyl)methanol features a dual aromatic system linked by a methylene bridge, combining the electronic properties of pyridine with the extended conjugation of a para-substituted phenyl ring. This rigid, planar scaffold enhances π-stacking potential and offers a stable platform for functionalization at the benzylic position. The molecule exhibits good solubility in common organic solvents and maintains stability under standard bench conditions.

Application

(4-(Pyridin-4-yl)phenyl)methanol serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of biaryl scaffolds via standard coupling reactions. Its benzyl alcohol functionality facilitates straightforward derivatization—such as oxidation to aldehydes or carboxylic acids—and exhibits good bench stability and ease of purification. The molecule functions effectively in Suzuki-Miyaura and Ullmann-type transformations, offering robust compatibility with diverse functional groups and supporting scalable synthesis workflows.

General Information

CAS No. 217192-22-8
Cat. No. CS-0157565
Purity ≥98%
MDL No. MFCD04114576
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₁NO
Molecular Weight 185.22
Synonym(s) (4-PYRID-4-YLPHENYL)METHANOL
SMILES C1=C(C=CC(=C1)C2=CC=NC=C2)CO

Computational Chemistry Data

TPSA 33.12
LogP 2.2409
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(4-(Pyridin-4-yl)phenyl)methanol

CAS No. 217192-22-8

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