(2R,4R)-Pentane-2,4-diylbis(bis(3,5-dimethylphenyl)phosphine)

Name: (2R,4R)-Pentane-2,4-diylbis(bis(3,5-dimethylphenyl)phosphine)
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 217648-63-0
Cat. No. CS-0698650
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2R,4R)-Pentane-2,4-diylbis(bis(3,5-dimethylphenyl)phosphine)|CS-0698650

Structure of 217648-63-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This chiral bisphosphine ligand features two phosphine groups tethered by a rigid pentane backbone, with each phosphorus atom flanked by sterically hindered 3,5-dimethylphenyl rings. The (2R,4R) stereochemistry ensures precise spatial control, enabling high selectivity in transition metal-catalyzed asymmetric transformations. Designed for robust performance under standard conditions, it delivers enhanced catalyst stability and reproducible enantioselectivity in cross-coupling and hydrogenation reactions.

Application

(2R,4R)-Pentane-2,4-diylbis(bis(3,5-dimethylphenyl)phosphine) serves as a chiral, bidentate phosphine ligand enabling efficient transition-metal-catalyzed cross-coupling reactions. Its sterically shielded aryl groups enhance stability and selectivity in palladium- and nickel-catalyzed processes, facilitating C–C bond formation under mild conditions. The ligand exhibits excellent functional group tolerance and ease of purification, making it well-suited for iterative synthesis and scale-up applications in medicinal chemistry and materials science.

General Information

CAS No. 217648-63-0
Cat. No. CS-0698650
Purity ≥98%
MDL No. None
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₇H₄₆P₂
Molecular Weight 552.71
Synonym(s) None
SMILES C[C@H](C[C@@H](C)P(C1=CC(C)=CC(C)=C1)C1=CC(C)=CC(C)=C1)P(C1=CC(C)=CC(C)=C1)C1=CC(C)=CC(C)=C1

Computational Chemistry Data

TPSA 0
LogP 8.88666
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Catalysis Asymmetric Synthesis Chiral Catalysts, Chiral Ligands, Chiral Reagents Hydrogenation

Catalysis Asymmetric Synthesis Chiral Catalysts, Chiral Ligands, Chiral Reagents Chiral Ligands (Other)

Catalysis Phosphorous Compounds Polydentate Phosphine Ligands

Key Words

217648-63-0 sigma217648-63-0 manufacturer217648-63-0 price217648-63-0 structure217648-63-0 SDSbuy 217648-63-0217648-63-0 supplier217648-63-0 uses217648-63-0 molecular weightprice of 217648-63-0217648-63-0 chemical name formula of 217648-63-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(2R,4R)-Pentane-2,4-diylbis(bis(3,5-dimethylphenyl)phosphine)

CAS No. 217648-63-0

Recommended Products