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CS-W001157 4
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(S)-3-(Methoxymethyl)morpholine hydrochloride

  • CAS No. 218594-76-4

  • Cat. No. CS-0103639
  • Purity≥97%
  • MDL No.MFCD09608107
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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(S)-3-(Methoxymethyl)morpholine hydrochloride|CS-0103639

Structure of 218594-76-4

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Description

(S)-3-(Methoxymethyl)morpholine hydrochloride is a chiral morpholine derivative featuring a methoxymethyl substituent at the 3-position, offering enhanced solubility and stability in aqueous and polar organic media. This bench-stable salt serves as a key building block in asymmetric synthesis, particularly for pharmaceutical intermediates and bioactive molecule scaffolds requiring defined stereochemistry.

Application

(S)-3-(Methoxymethyl)morpholine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through established functional group transformations. Its morpholine core provides favorable solubility and metabolic stability, while the methoxymethyl group offers orthogonal reactivity for selective derivatization. The hydrochloride salt enhances bench stability and facilitates purification, making it well-suited for scalable synthesis workflows.

General Information

  • CAS No. 218594-76-4
  • Cat. No. CS-0103639
  • Purity ≥97%
  • MDL No. MFCD09608107
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO₂
  • Molecular Weight 167.63
  • Synonym(s) (S)-3-Methoxymethyl-morpholine hydrochloride
  • SMILES COC[C@@H]1NCCOC1.[H]Cl

Computational Chemistry Data

  • TPSA   30.49
  • LogP   0.043
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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