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Structure of 21997-23-9
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5-Nitrobenzofuran-2(3H)-one features a fused bicyclic core with a nitro group at the 5-position, conferring strong electron-withdrawing character. This structural motif enables participation in cycloadditions and transition-metal-catalyzed couplings, serving as a key building block in heterocyclic synthesis. The compound exhibits stability under standard bench conditions and facilitates access to complex nitrogen-containing architectures.
5-Nitrobenzofuran-2(3H)-one serves as a versatile building block in medicinal chemistry, enabling efficient access to nitro-substituted benzofuran scaffolds. Its reactivity profile supports direct functionalization at the 5-position and facilitates transition metal-catalyzed coupling reactions. The molecule exhibits bench stability and tolerates diverse reaction conditions, making it well-suited for modular synthesis of heterocyclic intermediates and potential API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: