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Structure of 220629-00-5
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This chiral oxazole features a sterically hindered tert-butyl group and a quinolin-8-yl moiety, delivering enhanced stability and defined stereochemistry. It integrates readily into complex molecular architectures, particularly in medicinal chemistry scaffolds requiring rigid, electron-deficient heterocycles for target engagement.
(S)-4-(tert-Butyl)-2-(quinolin-8-yl)-4,5-dihydrooxazole serves as a versatile chiral building block for the synthesis of bioactive heterocycles. Its dihydrooxazole core exhibits robust bench stability and compatibility with standard functional group transformations. The tert-butyl group enhances solubility and facilitates purification, while the quinolin-8-yl moiety provides a rigid, planar scaffold useful in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: