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Structure of 220665-47-4
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This chiral diamine features two trifluoromethylphenyl groups flanking a rigid ethane backbone, enabling precise stereocontrol in asymmetric catalysis. The (1R,2R) configuration and N-methyl substitution enhance solubility and stability while maintaining high enantioselectivity in transition metal complexes.
(1R,2R)-N1,N2-Dimethyl-1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-diamine serves as a chiral diamine ligand in transition-metal-catalyzed asymmetric transformations. Its rigid, sterically defined framework enables high enantioselectivity in palladium- and nickel-catalyzed cross-coupling reactions. The trifluoromethyl aryl groups enhance electronic modulation and improve bench stability, while the N-methyl substituents reduce basicity and facilitate purification. This compound functions effectively in standard synthetic workflows requiring robust chiral control.
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GHS Pictogram :
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GHS No : GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H410
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: