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Structure of 220880-12-6
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4-(Trifluoromethyl)pyrimidine-5-carboxylic acid features a trifluoromethyl group at the 4-position and a carboxylic acid at the 5-position on a pyrimidine scaffold, delivering enhanced electron-withdrawing character and metabolic stability. This configuration supports direct incorporation into bioactive molecules, enabling efficient conjugation in medicinal chemistry and materials science applications.
4-(Trifluoromethyl)pyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct derivatization or conjugation. The molecule exhibits good bench stability and compatibility with common reaction conditions, making it well-suited for iterative synthesis workflows and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: