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CS-W001157 4
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1,3-Dibromo-2,2-dimethoxypropane

  • CAS No. 22094-18-4

  • Cat. No. CS-W005012
  • Purity≥98%
  • MDL No.MFCD00051792
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,3-Dibromo-2,2-dimethoxypropane|CS-W005012

Structure of 22094-18-4

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Description

1,3-Dibromo-2,2-dimethoxypropane delivers a robust difunctional bromination capability in organic synthesis. The geminal dimethoxy groups stabilize the adjacent carbon center, enhancing reactivity while maintaining bench stability. This reagent enables efficient α-bromination of carbonyl compounds and facilitates tandem substitution reactions under mild conditions.

Application

1,3-Dibromo-2,2-dimethoxypropane serves as a reliable dibrominating agent for enolizable carbonyl compounds and activated methylene groups, enabling efficient α,α′-dibromination under mild conditions. Its dimethoxy protection stabilizes the molecule against hydrolysis, enhancing bench stability and simplifying handling. The reagent exhibits high functional group tolerance and facilitates clean reaction profiles with minimal side products, making it particularly valuable in the synthesis of brominated intermediates for pharmaceutical and agrochemical applications.

General Information

  • CAS No. 22094-18-4
  • Cat. No. CS-W005012
  • Purity ≥98%
  • MDL No. MFCD00051792
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀Br₂O₂
  • Molecular Weight 261.94
  • Synonym(s) 1,3-Dibromoacetone Dimethyl Acetal
  • SMILES C(C(CBr)(OC)OC)Br

Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.7653
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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