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CS-W001157 4
Total: USD 88.00

(3-Phenoxyphenyl)boronic acid

  • CAS No. 221006-66-2

  • Cat. No. CS-0174529
  • Molecule weight214.02
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Phenoxyphenyl)boronic acid|CS-0174529

Structure of 221006-66-2

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General Information

  • CAS No. 221006-66-2
  • Cat. No. CS-0174529
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₁BO₃
  • Molecular Weight 214.02
  • Synonym(s) 3-Phenoxyphenylboronic acid
  • SMILES OB(O)C1=CC(OC2=CC=CC=C2)=CC=C1

Description

(3-Phenoxyphenyl)boronic acid features a phenoxy-substituted aryl boronate that integrates readily into Suzuki-Miyaura coupling reactions. The electron-rich aromatic system enhances reactivity, while the boronic acid moiety offers stability under standard conditions and compatibility with diverse functional groups.

Application

(3-Phenoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it well-suited for late-stage functionalization in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • EP1489077 A1, ; Page 31 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   1.1587
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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