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Structure of 2212021-60-6
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This tetrahydro-pyrazolopyridine derivative features a tert-butyl ester group and a fluoro-substituted aryl moiety, enabling precise tuning of solubility and metabolic stability. The 2,2-dimethoxyethylureido side chain enhances polarity and hydrogen-bonding capacity, while the sterically protected methyl groups contribute to conformational rigidity. This scaffold integrates well into medicinal chemistry campaigns targeting kinase inhibition and CNS-penetrant therapeutics under standard bench conditions.
tert-Butyl (S)-3-(3-(2,2-dimethoxyethyl)ureido)-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate serves as a versatile building block for the synthesis of pyrazolopyridine-based scaffolds. Its tert-butyl ester enables straightforward deprotection under mild acidic conditions, while the 2,2-dimethoxyethyl ureido group provides orthogonal handle for selective functionalization. The molecule exhibits robust bench stability and compatibility with standard coupling reactions, facilitating efficient access to biologically relevant heterocycles in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: