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Structure of 22126-44-9
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6-(Hydroxymethyl)uracil features a hydroxymethyl group appended to the C6 position of the uracil core, enhancing solubility and enabling site-specific conjugation in nucleic acid chemistry. This functionalized analog serves as a key building block for modified oligonucleotides, offering improved stability and compatibility with enzymatic synthesis workflows.
6-(Hydroxymethyl)uracil serves as a versatile uracil derivative enabling site-specific modifications in nucleoside and nucleotide synthesis. Its hydroxymethyl group facilitates efficient functionalization via oxidation to carboxylic acid or conversion to aldehyde handles, supporting conjugation strategies. The compound exhibits good bench stability and compatibility with standard protecting group protocols, making it a reliable building block for carbohydrate- and peptide-nucleic acid hybrid architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: