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Structure of 22190-33-6
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5-Bromoindoline features a bromine substituent at the 5-position of the indoline scaffold, enhancing its utility in transition-metal-catalyzed coupling reactions. This bench-stable heterocycle serves as a key intermediate in medicinal chemistry, where its electron-deficient character supports efficient functionalization.
5-Bromoindoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. Its bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the indoline core offers favorable stability and solubility for bench-scale synthesis. The molecule functions as a key intermediate in the development of kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: