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Structure of 22233-52-9
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3-Chloro-2-nitrobenzaldehyde features a strategically positioned nitro group and chlorine substituent that enhance electrophilicity at the aldehyde carbon. This electron-deficient aromatic scaffold enables efficient coupling in cross-coupling reactions and serves as a key intermediate in the synthesis of pharmaceuticals and functional dyes.
3-Chloro-2-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via condensation and cyclization reactions. Its ortho-nitro and chloro substituents provide complementary reactivity for nucleophilic substitution and electrophilic functionalization, while the aldehyde group facilitates imine formation and subsequent transformations. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring precise regiocontrol.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: