7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

Name: 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
Brand: ChemScene
Availability: InStock
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CAS No. 22246-18-0
Cat. No. CS-W010846
Purity≥98%
MDL No.MFCD06410891

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone|CS-W010846

Structure of 22246-18-0

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Description

Silver sulfate (Ag2SO4) is the disilver(I) salt of sulfuric acid. It participates in the TiO2-assisted photooxidation of substituted benzyltrimethylsilanes in acetonitrile. Diarylethanes were obtained in 50-74% yields. It has been reported as one of the common atmospheric silver corrosion product.Silver sulfate may be employed in the following studies:Iodination reagent in combination with iodine for the synthesis of iododerivatives.Synthesis of iodinated uredines.Preparation of silver sulfate reagent, which is required for the determination of Chemical Oxygen Demand (COD).

Application

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its hydroxyl group facilitates direct derivatization and enhances solubility, while the dihydroquinolinone core supports robust functionalization via electrophilic substitution and transition-metal-catalyzed coupling. The compound exhibits bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in API development and lead optimization.

General Information

CAS No. 22246-18-0
Cat. No. CS-W010846
Purity ≥98%
MDL No. MFCD06410891
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₉NO₂
Molecular Weight None
Synonym(s) 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
SMILES O=C1NC2=C(C=CC(O)=C2)CC1

Computational Chemistry Data

TPSA 49.33
LogP 1.2769
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317-H412
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Skeleton Aromatic heterocycle compounds Tetrahydroquinoline compounds

Key Words

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7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

CAS No. 22246-18-0

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