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Structure of 2228857-35-8
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Hydroxy-PEG4-C2-methyl ester features a hydroxyl-terminated polyethylene glycol chain of four ethylene oxide units, linked via a C2 spacer to a methyl ester group. This amphiphilic construct offers enhanced solubility in aqueous and organic media, enabling seamless integration into conjugation workflows. The terminal hydroxyl supports further derivatization, while the stable ester linkage resists premature hydrolysis under standard conditions.
Hydroxy-PEG4-C2-methyl ester serves as a versatile bifunctional building block for conjugation and solubilization in synthetic chemistry. The terminal hydroxyl group enables further derivatization, while the C2 methyl ester functions as a stable, easily cleavable linker under mild basic conditions. Its PEG4 spacer provides enhanced aqueous solubility and reduced aggregation, making it ideal for peptide, oligonucleotide, and small-molecule conjugates requiring improved pharmacokinetic profiles and compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: