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Structure of 2230803-78-6
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This iodomethyl-substituted oxabicyclic nitrile features a strained, electron-deficient scaffold that enables selective functionalization in complex molecular architectures. The pendant carbonitrile group enhances reactivity in cross-coupling processes, while the iodide serves as a high-efficiency handle for palladium-catalyzed transformations. Bench-stable and compatible with diverse reaction conditions, this reagent streamlines access to rigid, polarized frameworks in medicinal chemistry and materials synthesis.
1-(Iodomethyl)-2-oxabicyclo[2.1.1]hexane-4-carbonitrile serves as a versatile, bench-stable building block for the synthesis of functionalized heterocycles and bioactive scaffolds. The iodomethyl group enables efficient late-stage diversification via palladium-catalyzed cross-coupling reactions, while the nitrile and oxabicyclic framework provide orthogonal reactivity and structural rigidity. Its compatibility with standard synthetic protocols makes it ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H318-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: