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Structure of 223785-76-0
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1-(2,6-Dichloro-3-nitrophenyl)ethanone features a nitro-substituted aromatic core paired with a ketone-functionalized side chain, delivering high reactivity in electrophilic coupling reactions. The electron-deficient ring enhances its utility in C–C bond formation, while the dichloro substitution pattern ensures structural rigidity and improved solubility under standard conditions.
1-(2,6-Dichloro-3-nitrophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of substituted heterocycles and functionalized aryl scaffolds. Its dual electron-withdrawing groups (nitro and acetyl) enhance electrophilicity for nucleophilic aromatic substitution and facilitate downstream transformations such as reduction, coupling, and cyclization. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: