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CS-W001157 4
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2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite

  • CAS No. 2245842-16-2

  • Cat. No. CS-0199871
  • Molecule weight772.80
  • Purity≥98%
  • MDL No.MFCD22374068

*For research and further manufacturing use only, not for direct human use.

2'-Fluoro-5'-O-DMT-2'-deoxyinosine-3'-CE-phosphoramidite|CS-0199871

Structure of 2245842-16-2

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General Information

  • CAS No. 2245842-16-2
  • Cat. No. CS-0199871
  • Purity ≥98%
  • MDL No. MFCD22374068
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₀H₄₆FN₆O₇P
  • Molecular Weight 772.80
  • Synonym(s) None
  • SMILES COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C(NC=NC6=O)=C6N=C5)O4

Description

Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.

Safety Information

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GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H317-H319-H335-H360
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   145.98
  • LogP   7.04218
  • H_Acceptors   12
  • H_Donors   1
  • Rotatable_Bonds   17

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