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Structure of 2246373-43-1
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Methyl 3-bromo-1H-pyrazole-5-carboxylate features a brominated pyrazole core with a methyl ester handle, enabling direct incorporation into cross-coupling reactions. The electron-deficient pyrazole ring enhances reactivity in palladium-catalyzed transformations, while the bench-stable ester group simplifies handling and purification. This compound serves as a key intermediate for heterocyclic scaffolds in medicinal chemistry and agrochemical development.
Methyl 3-bromo-1H-pyrazole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions for the construction of substituted pyrazole scaffolds. The bromo group facilitates efficient C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the ester functionality supports further derivatization. Its bench-stable nature and compatibility with diverse functional groups make it ideal for medicinal chemistry and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: