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Structure of 2250216-93-2
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Boc-NH-PEG3-NHS ester features a trifunctional linkage: a Boc-protected amine, a three-unit PEG spacer, and a reactive NHS ester. This combination enables site-specific conjugation to primary amines under physiological conditions while maintaining solubility and stability. The PEG3 chain minimizes non-specific binding, enhancing performance in bioconjugation workflows. Ideal for labeling proteins, peptides, or surface-functionalizing nanoparticles with controlled hydrophilicity and reduced aggregation.
Boc-NH-PEG3-NHS ester serves as a versatile bifunctional linker for protein and peptide conjugation, combining the stability of the Boc protecting group with the reactivity of the NHS ester. The PEG3 spacer enhances solubility and reduces steric hindrance, enabling efficient coupling to primary amines under physiological conditions. Ideal for site-specific bioconjugation, it facilitates the synthesis of antibody-drug conjugates and peptide-protein hybrids with improved handling and purification characteristics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: