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CS-W001157 4
Total: USD 88.00

3-(Trifluoromethyl)benzoyl chloride

  • CAS No. 2251-65-2

  • Cat. No. CS-0012460
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Trifluoromethyl)benzoyl chloride|CS-0012460

Structure of 2251-65-2

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General Information

  • CAS No. 2251-65-2
  • Cat. No. CS-0012460
  • Purity ≥98%
  • MDL No. None
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄ClF₃O
  • Molecular Weight 208.56
  • Synonym(s) None
  • SMILES O=C(Cl)C1=CC=CC(C(F)(F)F)=C1

Application

3-(Trifluoromethyl)benzoyl chloride serves as a versatile acylating agent in synthetic organic chemistry, enabling efficient introduction of the electron-withdrawing trifluoromethylphenylcarbonyl group into diverse substrates. Its reactivity facilitates amide and ester formation under mild conditions, with enhanced stability compared to analogous acid chlorides. The compound exhibits good functional group tolerance and is particularly useful in constructing bioactive scaffolds found in pharmaceutical intermediates and agrochemicals.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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