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2-Phenylazetidine

  • CAS No. 22610-18-0

  • Cat. No. CS-0054345
  • Molecule weight133.19
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Phenylazetidine|CS-0054345

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General Information

  • CAS No. 22610-18-0
  • Cat. No. CS-0054345
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N
  • Molecular Weight 133.19
  • Synonym(s) 2-Phenylazetidine HCl
  • SMILES C1(C2=CC=CC=C2)NCC1

Description

2-Phenylazetidine is a strained heterocyclic amine featuring a reactive azetidine ring fused to a phenyl group. This scaffold imparts enhanced nucleophilicity and conformational rigidity, making it valuable for medicinal chemistry applications. The compound demonstrates good stability under standard conditions and integrates readily into complex molecular architectures.

Application

2-Phenylazetidine serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization protocols. Its strained azetidine core enhances reactivity in nucleophilic substitution and cycloaddition reactions, while the phenyl group provides structural rigidity and π-interaction potential. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.721
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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