6-Bromo-1,2,3,4-tetrahydroisoquinoline

Name: 6-Bromo-1,2,3,4-tetrahydroisoquinoline
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 226942-29-6
Cat. No. CS-W019599
Purity≥95%
MDL No.MFCD07374370

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1,2,3,4-tetrahydroisoquinoline|CS-W019599

Structure of 226942-29-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 226942-29-6
Cat. No. CS-W019599
Purity ≥95%
MDL No. MFCD07374370
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀BrN
Molecular Weight 212.09
Synonym(s) isoquinoline, 6-bromo-1,2,3,4-tetrahydro-
SMILES BrC1=CC2=C(CNCC2)C=C1

Description

6-Bromo-1,2,3,4-tetrahydroisoquinoline features a bromine substituent at the C6 position of the tetrahydroisoquinoline scaffold, delivering enhanced electrophilicity for downstream functionalization. This bench-stable heterocycle integrates readily into medicinal chemistry libraries and serves as a key intermediate in the synthesis of bioactive alkaloids and CNS-targeted compounds.

Application

6-Bromo-1,2,3,4-tetrahydroisoquinoline serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the aromatic ring via palladium-catalyzed cross-coupling reactions. Its bromine substituent offers high reactivity in Suzuki, Stille, and Negishi couplings, while the tetrahydroisoquinoline core provides structural rigidity and favorable pharmacophoric properties. The compound exhibits excellent bench stability and is readily purified by distillation or chromatography, facilitating integration into multi-step syntheses of bioactive molecules and heterocyclic scaffolds.

Synthesis

Route1
- 252331-63-8
- 726136-49-8
- ~49%
- In-stock
  
  226942-29-6
- In-stock
  
  75416-51-2
References
- WO2008/76954 A2, ; Page/Page column 50 ; WO 2008/076954 A2
Route2
- In-stock
  
  147497-32-3
- ~%
- In-stock
  
  226942-29-6
References
- US5977134 A1, ; US 5977134 A
Route3
- In-stock
  
  34784-05-9
- ~%
- In-stock
  
  226942-29-6
References
- WO2013/80222 A1, ; Page/Page column 39 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 12.03
LogP 2.0948
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Tetrahydroisoquinoline compounds

Key Words

6-Bromo-1,2,3,4-tetrahydroisoquinoline sigma6-Bromo-1,2,3,4-tetrahydroisoquinoline manufacturer6-Bromo-1,2,3,4-tetrahydroisoquinoline price6-Bromo-1,2,3,4-tetrahydroisoquinoline structure6-Bromo-1,2,3,4-tetrahydroisoquinoline SDSbuy 6-Bromo-1,2,3,4-tetrahydroisoquinoline6-Bromo-1,2,3,4-tetrahydroisoquinoline supplier6-Bromo-1,2,3,4-tetrahydroisoquinoline uses6-Bromo-1,2,3,4-tetrahydroisoquinoline molecular weightprice of 6-Bromo-1,2,3,4-tetrahydroisoquinoline6-Bromo-1,2,3,4-tetrahydroisoquinoline chemical name formula of 6-Bromo-1,2,3,4-tetrahydroisoquinoline

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromo-1,2,3,4-tetrahydroisoquinoline

CAS No. 226942-29-6

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words